Propofol | Propofol-Anesthetic-Sedation 500vials

Every ml of emulsion for infusion/implantation contains 10 mg of propofol.

200ml vial contains 2000 mg of propofol

400ml vial contains 4000 mg of propofol

500ml vial contains 5000 mg of propofol

Propofol/ml is a short-acting general intravenous sedative specialized for

• Induction and maintenance of general sedation in adults and young people
• Sedation
  for demonstrative and surgical surgeries, alone or in combination with
  local or provincial sedation in adults and children
• Sedation of ventilated patients

Dosage

Adults

General sedation in adults:

Acceptance of sedation:

For
acceptance of sedation, propofol must be titrated (about 20 – 40 mg of
propofol like clockwork) against the patient’s reaction until clinical
signs show the onset of sedation.

Most adult patients under the age of 55 will likely require 1.5 to 2.5 mg of propofol/kg of body weight.

In
patients above this age and in patients with ASA (American Society of
Anesthesiology) grades III and IV, particularly those with impaired
cardiac function, the prerequisites will generally be lower and the
total portion of Propofol may be reduced to at least 1 mg. of propofol.
/kg of body weight. Lower rates of Propofol administration should be
used (about 2 ml (20 mg propofol) at regular intervals).

Sedation Support:

To
maintain sedation, large doses of 4 to 12 mg of propofol/kg of body
weight/h must be administered. A reduced support portion of
approximately 4 mg propofol/kg body weight/h may be adequate during less
stressful surgeries, e.g., minor intrusive medical procedures.
Propofol may be decreased further depending on the severity of the patient’s condition and the sedative strategy undertaken.

Sedation in adults during focused attention:

When
used to provide sedation to ventilated patients in conditions of
focused attention, it is suggested that Propofol be administered in a
persistent mixture. The portion should be altered by the depth of
sedation required. Generally, good sedation is achieved with
organization rates in the range of 0.3 to 4.0 mg propofol/kg body
weight/h. Mixture doses greater than 4.0 mg of propofol/kg of body
weight/h are not suggested (see area 4.4 Special warnings and safe use).