Description
Methoxetamine, abbreviated as MXE, is a dissociative hallucinogen that
has been sold as a designer drug. It differs from many dissociatives
such as ketamine and phencyclidine that were developed as pharmaceutical
drugs for use as general anesthetics in that it was designed for grey
market distribution.
Methoxetamine is a near chemical analog of ketamine and PCP. Its use was
first publicly reported in 2010. MXE is an arylcyclohexylamine. It acts
mainly as a selective NMDA receptor antagonist, similarly to other
arylcyclohexylamines like ketamine and PCP. 3-MeO-2′-Oxo-PCE (commonly
known as Methoxetamine, MXE, Mexxy, among others) is a dissociative
substance of the arylcyclohexylamine class that produces ketamine-like
dissociative effects when administered.
It is structurally related to ketamine,buy methamphetamine online Buy
MXE Online MXE is an arylcyclohexylamine. It is a derivative of
eticyclidine (PCE) and 3-methoxyeticyclidine (3-MeO-PCE) and is also
known as 3-methoxy-2′-oxo-PCE. It is closely related structurally to
ketamine, and more distantly to PCP. MXE is reported to have a similar
effect to ketamine, with increased potency and duration. It was often
believed to possess opioid properties due to its structural similarity
to 3-HO-PCP, but this assumption is not supported by data, which shows
insignificant affinity for the ?-opioid receptor by the compound.
Recreational use of MXE has been associated with hospitalisations from
high and/or combined consumption in the US and UK. Acute reversible
cerebellar toxicity has been documented in three cases of hospital
admission due to MXE overdose, lasting for between one and four days
after exposure.
MXE may be an effective, fast-acting antidepressant like ketamine.
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